Brain compression without global neuronal loss in meningiomas: whole-brain proton MR spectroscopy report of 2 cases.

نویسندگان

  • Benjamin A Cohen
  • Edmond A Knopp
  • Henry Rusinek
  • Songtao Liu
  • Oded Gonen
چکیده

We report the findings from whole-brain proton MR spectroscopy, quantifying the neuronal marker N-acetylaspartate (NAA), for 2 presurgical meningioma patients and 10 healthy controls. The patients' whole-brain NAA (WBNAA) concentrations were considerably elevated (3+ SDs) compared with healthy controls when excluding the tumors from brain volume; WBNAA levels normalized following correction to approximate "preneoplastic" brain size. These results suggest global neuronal preservation in these 2 patients while their brains were compressed by large, slowly growing, extra-axial masses.

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عنوان ژورنال:
  • AJNR. American journal of neuroradiology

دوره 26 9  شماره 

صفحات  -

تاریخ انتشار 2005